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A dedicated New York psychiatrist Sam Foster urgently attempts to stop a secretive and unusual young patient he inherited, Henry Lethem, from carrying out a planned suicide on the eve of his 21st birthday. But Sam's investigation of Henry has reality-shattering effects on the psychiatrist. As Sam is drawn deeper into the web of Henry's life--and then into the labyrinth of his subconscious--it puts stress on Sam's relationship with his artist girlfriend and former patient Lila. But soon Sam's own tightly-held grip on the rational world begins to melt away. Faced with increasingly surreal encounters and a Manhattan transformed into a wildly shifting dreamscape, Sam can no longer figure out what is true and what is happening only in his head, nor where he begins and Henry ends. (officiële tekst van distribiteur)